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Anti-NPM2 Antibody

     
  • WB - Anti-NPM2 Antibody ABO11299
    Anti-NPM2 antibody, ABO11299, Western blottingLane 1: HELA Cell LysateLane 2: U87 Cell LysateLane 3: A549 Cell LysateLane 4: SMMC Cell Lysate
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q86SE8
Host Rabbit
Reactivity Human
Clonality Polyclonal
Format Lyophilized
Description Rabbit IgG polyclonal antibody for Nucleoplasmin-2(NPM2) detection. Tested with WB in Human.
Reconstitution Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Additional Information
Gene ID 10361
Other Names Nucleoplasmin-2, NPM2
Calculated MW 24152 MW KDa
Application Details Western blot, 0.1-0.5 µg/ml, Human
Subcellular Localization Nucleus . Found in the oocyte nucleus before nuclear membrane breakdown, after which it is redistributed to the cytoplasm. .
Protein Name Nucleoplasmin-2
Contents Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Immunogen A synthetic peptide corresponding to a sequence at the N-terminus of human NPM2(25-43aa QERRTWTFRPQLEGKQSCR).
Purification Immunogen affinity purified.
Cross Reactivity No cross reactivity with other proteins
Storage At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
Protein Information
Name NPM2
Function Core histones chaperone involved in chromatin reprogramming, specially during fertilization and early embryonic development. Probably involved in sperm DNA decondensation during fertilization.
Cellular Location Nucleus. Note=Found in the oocyte nucleus before nuclear membrane breakdown, after which it is redistributed to the cytoplasm.
Citations (0)

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Background

NPM2(Nucleophosmin/Nucleoplasmin Family Member 2), Burns et al.(2003) mapped the mouse Npm2 gene to chromosome 14. Burns et al.(2003) found that female Npm2-null mice showed defects in preimplantation embryo development, with abnormalities in oocyte and early embryonic nuclei.

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$ 240.00
Cat# ABO11299
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