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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-SLC1A4 Antibody   

Anti-SLC1A4 Antibody

     
  • WB - Anti-SLC1A4 Antibody ABO11496
    Anti-SLC1A4 antibody, ABO11496, Western blottingLane 1: U87 Cell LysateLane 2: Rat Brain Tissue LysateLane 3: Mouse Brain Tissue Lysate
  • IHC - Anti-SLC1A4 Antibody ABO11496
    Anti-SLC1A4 antibody, ABO11496, IHC(P)IHC(P): Human Intestinal Cancer Tissue
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession P43007
Host Rabbit
Reactivity Human, Mouse, Rat
Clonality Polyclonal
Format Lyophilized
Description Rabbit IgG polyclonal antibody for Neutral amino acid transporter A(SLC1A4) detection. Tested with WB, IHC-P in Human;Mouse;Rat.
Reconstitution Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Additional Information
Gene ID 6509
Other Names Neutral amino acid transporter A, Alanine/serine/cysteine/threonine transporter 1, ASCT-1, SATT, Solute carrier family 1 member 4, SLC1A4, ASCT1, SATT
Calculated MW 55723 MW KDa
Application Details Immunohistochemistry(Paraffin-embedded Section), 0.5-1 µg/ml, Human, Rat, Mouse, By Heat
Western blot, 0.1-0.5 µg/ml, Human, Mouse, Rat
Subcellular Localization Membrane ; Multi-pass membrane protein . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Tissue Specificity Expressed mostly in brain, muscle, and pancreas but detected in all tissues examined.
Protein Name Neutral amino acid transporter A
Contents Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Immunogen A synthetic peptide corresponding to a sequence at the C-terminus of human SLC1A4(495-512aa EAIPNCKSEEETSPLVTH), different from the related rat and mouse sequences by one amino acid.
Purification Immunogen affinity purified.
Cross Reactivity No cross reactivity with other proteins
Storage At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
Protein Information
Name SLC1A4
Synonyms ASCT1, SATT
Function Transporter for alanine, serine, cysteine, and threonine. Exhibits sodium dependence.
Cellular Location Membrane; Multi-pass membrane protein Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV
Tissue Location Expressed mostly in brain, muscle, and pancreas but detected in all tissues examined
Research Areas
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Background

Neutral amino acid transporter A, also called SLC1A4 or ASCT1, is a protein that in humans is encodes by the SLC1A4 gene. The SLC1A4 gene is mapped to chromosome 2p14 based on an alignment of the SLC1A4 sequence with the genomic sequence(GRCh37). ASCT1 does not transport glutamate or aspartate but alanine, serine, cysteine, and threonine instead. It is found that the ASCT1 transporter functions primarily as an amino acid exchanger. Transport is associated with a chloride channel activity that is thermodynamically uncoupled from animo acid transport. This gene also exhibits sodium dependence.

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$ 280.00
Cat# ABO11496
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