Anti-SLC16A4 Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P |
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Primary Accession | O15374 |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Clonality | Polyclonal |
Format | Lyophilized |
Description | Rabbit IgG polyclonal antibody for Monocarboxylate transporter 5(SLC16A4) detection. Tested with WB, IHC-P in Human;Mouse;Rat. |
Reconstitution | Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
Gene ID | 9122 |
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Other Names | Monocarboxylate transporter 5, MCT 5, Monocarboxylate transporter 4, MCT 4, Solute carrier family 16 member 4, SLC16A4, MCT4, MCT5 |
Calculated MW | 54022 MW KDa |
Application Details | Immunohistochemistry(Paraffin-embedded Section), 0.5-1 µg/ml, Human, Rat, Mouse, By Heat Western blot, 0.1-0.5 µg/ml, Human, Rat, Mouse |
Subcellular Localization | Cell membrane; Multi-pass membrane protein. |
Protein Name | Monocarboxylate transporter 5 |
Contents | Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
Immunogen | A synthetic peptide corresponding to a sequence at the N-terminus of human SLC16A4(134-148aa VVTTKYFKKRLALST), different from the related rat and mouse sequences by two amino acids. |
Purification | Immunogen affinity purified. |
Cross Reactivity | No cross reactivity with other proteins |
Storage | At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing. |
Name | SLC16A4 |
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Synonyms | MCT4, MCT5 |
Function | Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity). |
Cellular Location | Cell membrane; Multi-pass membrane protein. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Monocarboxylate transporter 5, also called Solute carrier family 16 member 4 or MCT4, is a protein that in humans is encodes by the SLC16A4 gene. This gene is mapped to 1p13.3. It acts as the proton-linked monocarboxylate transporter. This gene catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate.
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