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Anti-CD23/FCER2 Antibody

     
  • IHC - Anti-CD23/FCER2 Antibody ABO11772
    Anti-CD23 Picoband antibody, ABO11772-1.JPGIHC(P): Human Tonsil Tissue
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  • IHC - Anti-CD23/FCER2 Antibody ABO11772
    Anti-CD23 Picoband antibody, ABO11772-2.JPGIHC(P): Mouse Spleen Tissue
    detail
  • IHC - Anti-CD23/FCER2 Antibody ABO11772
    Anti-CD23 Picoband antibody, ABO11772-3.JPGIHC(P): Rat Spleen Tissue
    detail
  • WB - Anti-CD23/FCER2 Antibody ABO11772
    Anti-CD23 Picoband antibody, ABO11772-4.jpgAll lanes: Anti-CD23(ABO11772) at 0.5ug/mlWB: Mouse Liver Tissue Lysate at 40ugPredicted bind size: 37KDObserved bind size: 37KD
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IHC-F
Primary Accession P20693
Host Rabbit
Reactivity Human, Mouse, Rat
Clonality Polyclonal
Format Lyophilized
Description Rabbit IgG polyclonal antibody for Low affinity immunoglobulin epsilon Fc receptor(FCER2) detection. Tested with WB, IHC-P, IHC-F in Human;Mouse;Rat.
Reconstitution Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Additional Information
Gene ID 14128
Other Names Low affinity immunoglobulin epsilon Fc receptor, Fc-epsilon-RII, Lymphocyte IgE receptor, CD23, Fcer2, Fcer2a
Calculated MW Langerhans cells KDa
Application Details Immunohistochemistry(Frozen Section), 0.5-1 µg/ml, Mouse, -
Immunohistochemistry(Paraffin-embedded Section), 0.5-1 µg/ml, Human, Mouse, Rat, By Heat
Western blot, 0.1-0.5 µg/ml, Mouse
Subcellular Localization and macrophages. As part of a mapping of multiple probes to specific bands on chromosome 19 by fluorescence in situ hybridization
Tissue Specificity the FCE2 gene was assigned to 19p13.3. CD23 (FCE2) is a key molecule for B-cell activation and growth. It is the low-affinity receptor for IgE. The truncated molecule can be secreted
Source then functioning as a potent mitogenic growth factor."
Protein Name sc 13940|sc 31574|sc 7426|sc 365524
Contents Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Immunogen E.coli-derived mouse CD23 recombinant protein (Position: E50-P331). Mouse CD23 shares 52% amino acid (aa) sequence identity with human CD23.
Purification Immunogen affinity purified.
Cross Reactivity No cross reactivity with other proteins
Storage At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
Sequence Similarities Low affinity immunoglobulin epsilon Fc receptor;Fc-epsilon-RII;Lymphocyte IgE receptor;CD23;Fcer2;Fcer2a;
Protein Information
Name Fcer2
Synonyms Fcer2a
Function Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B cells. On B cells, initiates IgE-dependent antigen uptake and presentation to T cells. On macrophages, upon IgE binding and antigen cross-linking induces intracellular killing of parasites through activation of L-Arginine-nitric oxide pathway.
Cellular Location Cell membrane; Single-pass type II membrane protein. Cell membrane; Lipid- anchor. Secreted {ECO:0000250|UniProtKB:P06734}
Research Areas
Citations (0)
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Background

CD23, also known as Fc epsilon RII, or FcÎ µRII, is the low-affinity" receptor for IgE

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$ 280.00
Cat# ABO11772
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