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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   Anti-CNTF Picoband Antibody   

Anti-CNTF Picoband Antibody

     
  • IHC - Anti-CNTF Picoband Antibody ABO11783
    Anti-CNTF Picoband antibody, ABO11783-1.JPGIHC(P): Mouse Brain Tissue
  • IHC - Anti-CNTF Picoband Antibody ABO11783
    Anti-CNTF Picoband antibody, ABO11783-2.JPGIHC(P): Rat Brain Tissue
  •  - Anti-CNTF Picoband Antibody ABO11783
    Anti-CNTF Picoband antibody, ABO11783-3.jpgAll lanes: Anti-CNTF(ABO11783) at 0.5ug/mlLane 1: PC-12 Whole Cell Lysate at 40ugLane 2: NRK Whole Cell Lysate at 40ugLane 3: RH35 Whole Cell Lysate at 40ugLane 4: Rat Brain Tissue Lysate at 40ugLane 5: Rat Liver Tissue Lysate at 40ugLane 6: Rat Spleen Tissue Lysate at 40ugLane 7: Rat Testis Tissue Lysate at 40ugPredicted bind size: 23KDObserved bind size: 23KD
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P20294
Host Rabbit
Reactivity Mouse, Rat
Clonality Polyclonal
Format Lyophilized
Description Rabbit IgG polyclonal antibody for Ciliary neurotrophic factor(CNTF) detection. Tested with WB, IHC-P, ELISA in Mouse;Rat.
Reconstitution Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Additional Information
Gene ID 25707
Other Names Ciliary neurotrophic factor, CNTF, Cntf
Calculated MW 22854 MW KDa
Application Details ELISA , 0.1-0.5 µg/ml, Rat, -
Immunohistochemistry(Paraffin-embedded Section), 0.5-1 µg/ml, Mouse, Rat, By Heat
Western blot, 0.1-0.5 µg/ml, Rat
Subcellular Localization Cytoplasm.
Tissue Specificity Nervous system.
Protein Name Ciliary neurotrophic factor
Contents Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Immunogen E. coli-derived rat CNTF recombinant protein (Position: A2-M200). Rat CNTF shares 84% and 95% amino acid (aa) sequences identity with human and mouse CNTF, respectively.
Purification Immunogen affinity purified.
Cross Reactivity No cross reactivity with other proteins
Storage At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
Protein Information
Name Cntf
Function CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
Cellular Location Cytoplasm.
Tissue Location Nervous system.
Research Areas
Citations (0)

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Background

Ciliary neurotrophic factor is a protein that in humans is encoded by the CNTF gene. The protein encoded by this gene is a polypeptide hormone andnerve growth factor whose actions have mainly been studied in the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neural populations includingastrocytes. It is mapped to 11q12.1. In addition to neurotrophic effects on parasympathetic neurons, CNTF was shown to have activities on sympathetic and sensory neurons. CNTF appears not to be involved in motor neuron survival during development. human CNTF has a trophic influence on degenerating striatal neurons as well as on critical nonstriatal regions. CNTF plays a role in a cardiac signal transduction pathway that regulates obesity-related left ventricular hypertrophy.

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$ 280.00
Cat# ABO11783
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