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Anti-Fos B Antibody

     
  • WB - Anti-Fos B Antibody ABO12763
    Anti- Fos B antibody, ABO12763, Western blottingAll lanes: Anti Fos B (ABO12763) at 0.5ug/mlLane 1: Rat Kidney Tissue Lysate at 50ugLane 2: HEPG2 Whole Cell Lysate at 40ugPredicted bind size: 36KDObserved bind size: 36KD
  • IHC - Anti-Fos B Antibody ABO12763
    Anti- Fos B antibody, ABO12763, IHC(P)IHC(P): Mouse Intestine Tissue
  • IHC - Anti-Fos B Antibody ABO12763
    Anti- Fos B antibody, ABO12763, IHC(P)IHC(P): Rat Intestine Tissue
  • IHC - Anti-Fos B Antibody ABO12763
    Anti- Fos B antibody, ABO12763, IHC(P)IHC(P): Human Pancreatic Cancer Tissue
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession P53539
Host Rabbit
Reactivity Human, Mouse, Rat
Clonality Polyclonal
Format Lyophilized
Description Rabbit IgG polyclonal antibody for Protein fosB(FOSB) detection. Tested with WB, IHC-P in Human;Mouse;Rat.
Reconstitution Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Additional Information
Gene ID 2354
Other Names Protein fosB, G0/G1 switch regulatory protein 3, FOSB, G0S3
Calculated MW 35928 MW KDa
Application Details Immunohistochemistry(Paraffin-embedded Section), 0.5-1 µg/ml, Human, Mouse, Rat, By Heat
Western blot, 0.1-0.5 µg/ml, Human, Rat
Subcellular Localization Nucleus.
Protein Name Protein fosB
Contents Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Immunogen A synthetic peptide corresponding to a sequence at the C-terminus of human Fos B (264-291aa LPFQTSQDAPPNLTASLFTHSEVQVLGD), different from the related mouse sequence by two amino acids.
Purification Immunogen affinity purified.
Cross Reactivity No cross reactivity with other proteins
Storage At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
Sequence Similarities Belongs to the bZIP family. Fos subfamily.
Protein Information
Name FOSB
Synonyms G0S3
Function FosB interacts with Jun proteins enhancing their DNA binding activity.
Cellular Location Nucleus.
Research Areas
Citations (0)

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Background

FOSB, FBJ murine osteosarcoma viral oncogene homolog B, is a protein that, in humans, is encoded by the FOSB gene. FOSB is a member of Fos gene family which consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. The FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. The FOSB gene is mapped to 19q13.32. Delta FOSB is a truncated splice variant of FOSB. Delta FosB has been implicated in the development of drug addiction and control of the reward system in the brain, and is linked to changes in a number of other gene products such as CREB and sirtuins. Delta FosB also regulates the commitment of mesenchymal precursor cells to the adipocyte or osteoblast lineage.

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$ 280.00
Cat# ABO12763
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