Anti-CD252 Picoband Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | P43488 |
Host | Rabbit |
Reactivity | Mouse |
Clonality | Polyclonal |
Format | Lyophilized |
Description | Rabbit IgG polyclonal antibody for CD252 detection. Tested with WB, ELISA(Cap) in Mouse. |
Reconstitution | Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
Gene ID | 22164 |
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Other Names | Tumor necrosis factor ligand superfamily member 4, OX40 ligand, OX40L, CD252, Tnfsf4, Ox40l, Txgp1l |
Calculated MW | 22255 Da |
Application Details | Western blot, 0.1-0.5 µg/ml ELISA(Cap), 0.1-0.5 µg/ml |
Subcellular Localization | Membrane; Single-pass type II membrane protein. |
Contents | Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. |
Immunogen | E. coli-derived mouse CD252 recombinant protein (Position: Q49-L198). |
Cross Reactivity | No cross reactivity with other proteins. |
Storage | At -20˚C; for one year. After r˚Constitution, at 4˚C; for one month. It˚Can also be aliquotted and stored frozen at -20˚C; for a longer time. Avoid repeated freezing and thawing. |
Name | Tnfsf4 |
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Synonyms | Ox40l, Txgp1l |
Function | Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production. |
Cellular Location | Membrane; Single-pass type II membrane protein. |
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Provided below are standard protocols that you may find useful for product applications.
Background
OX40L(TNFSF4) is the ligand for CD134 and is expressed on such cells as DC2s (a subtype of dendritic cells) enabling amplification of Th2 cell differentiation. This gene encodes a cytokine of the tumor necrosis factor (TNF) ligand family. The encoded protein functions in T cell antigen-presenting cell (APC) interactions and mediates adhesion of activated T cells to endothelial cells. Polymorphisms in this gene have been associated with Sjogren's syndrome and systemic lupus erythematosus. Alternative splicing results in multiple transcript variants.
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