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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   Caspase-5 Antibody   

Caspase-5 Antibody

Rabbit Polyclonal Antibody

  • WB - Caspase-5 Antibody ABV10021
    Western blot analysis of Caspase-5 in rat kidney tissue lysate. Caspase-5 intermediate (30 kDa) and full cleaved (20 kDa) fragments were detected.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P51878
Other Accession NP_004338
Reactivity Human, Mouse, Rat, Hamster, Monkey, Bovine
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 49736 Da
Additional Information
Gene ID 838
Application & Usage Western blotting (0.5-4ag/ml). However, the optimal conditions should be determined individually. The affinity purified antibody preferentially detects the intermediate (32 kDa) and the fully (20 kDa) cleaved caspase-5.
Other Names CASP-5, ICH-3 protease, TY protease, ICH3
Target/Specificity Caspase-5
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.2 mg/ml) affinity purified rabbit anti-caspase-5 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA and 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsCaspase-5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CASP5
Synonyms ICH3
Function Mediator of programmed cell death (apoptosis).
Tissue Location Expressed in barely detectable amounts in most tissues except brain, highest levels being found in lung, liver and skeletal muscle
Research Areas
Citations (0)

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Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase-5 is also known as Ich-3 and ICErel-III and can proteolytically processed by granzyme B. Over expression of caspase-5 induces apoptosis in Rat-1 and HeLa cells, which can be inhibited by CrmA and Bcl-2.

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$ 245.00
Cat# ABV10021
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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