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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   Bok Antibody   

Bok Antibody

Rabbit Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UMX3
Other Accession EAW71269
Reactivity Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 23280 Da
Additional Information
Gene ID 666
Application & Usage Western blot analysis (0.5-4 µg/ml).
Other Names Bcl-2-related ovarian killer
Target/Specificity Bok
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.2 mg/ml) peptide affinity purified rabbit anti-Bok polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsBok Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name BOK
Synonyms BCL2L9
Function Induces apoptosis in a manner dependent on BAX and BAK.
Cellular Location Endoplasmic reticulum membrane; Single-pass membrane protein. Golgi apparatus membrane; Single-pass membrane protein. Note=The transmembrane domain is necessary and sufficient for Golgi and ER targeting
Tissue Location Expressed in brain, liver, appendix and lymphoid tissues.
Research Areas
Citations (0)

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Bok (Bcl-2-related ovarian killer) is a pro-apoptotic Bcl-2 family protein identified in the ovary based on its dimerization with the anti-apoptotic protein Mcl-1. In addition to the Bcl-2 homology (BH) domains 1 and 2 and the transmembrane sequence, Bok also has a BH3 domain believed to be important for dimerization with selective anti-apoptotic Bcl-2 proteins and cell killing. Bok interacts strongly with some (Mcl-1, BHRF1, and Bfl-1) but not other (Bcl-2, Bcl-xL, and Bcl-w) anti-apoptotic members. In addition, cell killing induced by Bok was suppressed following coexpression with Mcl-1 and BHRF1, but not with Bcl-2, further indicating that Bok heterodimerized only with selective anti-apoptotic Bcl-2 proteins. Bok was highly expressed in the ovary, testis and uterus.

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$ 285.00
Cat# ABV10032
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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