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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Cytochrome P450 Antibody   

Cytochrome P450 Antibody

Rabbit Polyclonal Antibody

     
  • WB - Cytochrome P450 Antibody ABV10060-30
    Western blot analysis of cytochrome P450 using Rat kidney tissue lysate.
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P05181
Other Accession NP_000764
Reactivity Human, Mouse, Rat, Dog
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 56849 Da
Additional Information
Gene ID 1571
Application & Usage Western blotting (0.5-4 µg/ml) .However, the optimal conditions should be determined individually. The antibody detects ~58kDa cytochrome P450 IIE1 from samples of human, mouse, rat and dog origins.
Other Names AHH , AHRR, CYP1A1 , CP11 , CYP1, P1-450, CYPIA1, P450-C, , P450DX, P450-P1
Target/Specificity Cytochrome p450
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5 mg/ml) purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA and 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsCytochrome P450 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CYP2E1
Synonyms CYP2E
Function Metabolizes several precarcinogens, drugs, and solvents to reactive metabolites. Inactivates a number of drugs and xenobiotics and also bioactivates many xenobiotic substrates to their hepatotoxic or carcinogenic forms.
Cellular Location Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein
Research Areas
Citations (0)

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Background

Cytochrome P450 is mainly found in liver, and can metabolize a wide range of compounds such as organic solvents, acetaminophen, dimethylnitrosoamine and aliphatic alcohol, which have certain toxicological effects in humans. Ethanol-induced cytochrome P450 IIE1 is considered to be one of the major causes of oxidative stress in the liver following ethanol treatment.

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$ 89.00
$ 245.00
Cat# ABV10060-30
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