|Reactivity||Human, Mouse, Rat|
|Calculated MW||28908 Da|
|Positive Control||Jurkat cell lysate|
|Application & Usage||Western Blot analysis (1 µg/ml). However, the optimal concentrations should be determined individually. Blocking peptide is available separately.|
|Other Names||TCF3 fusion partner homolog, Protein amida, Tfpt, Amida|
|Formulation||100 µg (0.5 mg/ml) affinity purified rabbit anti- TCF3/E2A polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal.|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||TCF3/E2A Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Appears to promote apoptosis in a p53/TP53-independent manner.|
|Tissue Location||Ubiquitously expressed. Abundant in the brain.|
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Provided below are standard protocols that you may find useful for product applications.
Heterodimers between TCF3 and tissue specific basic helix loop helix (bHLH) proteins play important roles in determining tissue specific cell fate during embryogenesis, like muscle or early B cell differentiation. Dimers bind DNA on E box motifs: 5' CANNTG 3'.Binds to the kappa E2 site in the kappa immunoglobulin gene enhancer.
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