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Proinsulin Antibody (Clone HPI-B5)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC, E |
|---|---|
| Primary Accession | P01308 |
| Reactivity | Human, Pig, Bovine |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | Mouse IgG1 |
| Clone Names | HPI-B5 |
| Calculated MW | 11981 Da |
| Gene ID | 3630 |
|---|---|
| Application & Usage | The antibody can be used for indirect ELISA, WB and IHC. |
| Other Names | Proinsulin |
| Target/Specificity | ProInsulin |
| Antibody Form | Liquid |
| Appearance | Colorless liquid |
| Formulation | 100 µg (1.0 mg/ml) purified mouse monoclonal antibody supplied in PBS with 0.05% (W/V) sodium azide. |
| Handling | The antibody solution should be gently mixed before use. |
| Reconstitution & Storage | -20 °C |
| Background Descriptions | |
| Precautions | Proinsulin Antibody (Clone HPI-B5) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | INS |
|---|---|
| Function | Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. |
| Cellular Location | Secreted. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Proinsulin is a prohormone precursor to Insulin, made by the pancreas in response to increased blood s µgar. Proinsulin is 39 amino acids longer than the mature Insulin, of which 4 are completely lost and the remaining 35 forms the C-peptide. The measurement of Proinsulin in serum provides a useful, valuable information for the diagnosis of insulinomas. Proinsulin levels have also been shown to be elevated in non-insulin dependent diabetics (NIDDM), in insulin dependent diabetics (IDDM) and other clinical situations. The antibody recognizes insulin and recombinant proinsulin, but does not react with synthetic C-peptide.
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