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MAK10 antibody

Rabbit Polyclonal Antibody

  • WB - MAK10 antibody ABV10105
    Western blot analysis of MADK10 using rat kidney tissue lysate
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6DKG0
Reactivity Human, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 83210 Da
Additional Information
Gene ID 64472
Positive Control Rat kidney tissue lysate
Application & Usage Western blotting (2-4 µg/ml). However, the optimal conditions should be determined individually.
Other Names Corneal wound-healing-related protein, Embryonic growth-associated protein, Protein MAK10 homolog
Target/Specificity MAK10
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5 mg/ml) affinity purified rabbit anti-MAK10 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsMAK10 antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Naa35
Synonyms Egap, Emb8, Mak10
Function Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues. Involved in regulation of apoptosis and proliferation of smooth muscle cells.
Cellular Location Cytoplasm.
Tissue Location Expressed in primary spermatocytes, basal epidermis, interstitial fibroblasts of skeletal muscle, and intestinal crypts.
Citations (0)

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MAK10 protein regulates the proliferation of smooth muscle cells. The mammalian homologue of yeast MAK10, also known as EGAP, is one subunit of a novel N-terminal acetyltransferase (NAT) that is highly conserved among vertebrate species. It is expressed in a variety of tissues in the developing rat embryo but restricted in expression in the adult, remaining detectable only in tissues undergoing continual cell renewal or in cells responding to pathological injury. The MAK10-NAT complex is an essential regulatory enzyme controlling the function of a subset of proteins required for embryonic growth control and vessel development.

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$ 245.00
Cat# ABV10105
(40 western blots)
Availability: 5-7days
Bulk Size
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