|Calculated MW||49880 Da|
|Positive Control||Rat kidney tissue lysate|
|Application & Usage||The antibody can be used in Western Blot analysis (4-10 µg/ml). However, the optimal concentrations should be determined individually. Blocking peptide is available separately.|
|Other Names||Glial fibrillary acidic protein|
|Formulation||100 µg (0.5 mg/ml) affinity purified rabbit anti - GFAP polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal.|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||GFAP Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||GFAP, a class-III intermediate filament, is a cell- specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.|
|Cellular Location||Cytoplasm. Note=Associated with intermediate filaments|
|Tissue Location||Expressed in cells lacking fibronectin.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
GFAP, Glial fibillary acidic protein is an intermediate filament protein. It was found in astrocytes cells as a cell specific marker in the central nervous system development. GFAP is defective in Alexander disease. But it is highly expressed in Astrogliosis which is a result of some diseases, such as AIDS, dementia and inflammatory demyelination diseases.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.