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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   SLAM/CD150 Antibody   

SLAM/CD150 Antibody

Rabbit Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q13291
Reactivity Human, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 37231 Da
Additional Information
Gene ID 6504
Positive Control Jurkat cell lysate
Application & Usage Western blotting (3-6 mg/ml). However, the optimal concentrations should be determined individually.
Other Names Cdw150 antibody, Estm51 antibody, Ipo 3 antibody, IPO-3 antibody, Ipo3 antibody, MGC151472 antibody, MGC151476 antibody, RGD1560634 antibody, Signaling lymphocytic activation molecule antibody, Signaling lymphocytic activation molecule family member 1 antibody, Signaling lymphocytic activation molecule precursor antibody, Slaf1 antibody
Target/Specificity SLAM/CD150
Antibody Form Liquid
Appearance Colorless liquid
Formulation 200 mg (0.5 mg/ml) purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsSLAM/CD150 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms SLAM
Function High-affinity self-ligand important in bidirectional T- cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.
Cellular Location Cell membrane; Single-pass type I membrane protein. Note=Present on the surface of B-cells and T-cells
Tissue Location Constitutively expressed on peripheral blood memory T-cells, T-cell clones, immature thymocytes and a proportion of B-cells, and is rapidly induced on naive T-cells after activation
Research Areas
Citations (0)

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Signaling lymphocytic activation molecule (SLAM/CD150) is expressed at hematopoietic tissue, such as memory T-cells, as well as at immature thymocytes. It has high-affinity self-ligand ability and plays an important role in interaction of T and B cells.

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$ 265.00
Cat# ABV10179
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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