|Calculated MW||37231 Da|
|Positive Control||Jurkat cell lysate|
|Application & Usage||Western blotting (3-6 mg/ml). However, the optimal concentrations should be determined individually.|
|Other Names||Cdw150 antibody, Estm51 antibody, Ipo 3 antibody, IPO-3 antibody, Ipo3 antibody, MGC151472 antibody, MGC151476 antibody, RGD1560634 antibody, Signaling lymphocytic activation molecule antibody, Signaling lymphocytic activation molecule family member 1 antibody, Signaling lymphocytic activation molecule precursor antibody, Slaf1 antibody|
|Formulation||200 mg (0.5 mg/ml) purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||SLAM/CD150 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||High-affinity self-ligand important in bidirectional T- cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein. Note=Present on the surface of B-cells and T-cells|
|Tissue Location||Constitutively expressed on peripheral blood memory T-cells, T-cell clones, immature thymocytes and a proportion of B-cells, and is rapidly induced on naive T-cells after activation|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Signaling lymphocytic activation molecule (SLAM/CD150) is expressed at hematopoietic tissue, such as memory T-cells, as well as at immature thymocytes. It has high-affinity self-ligand ability and plays an important role in interaction of T and B cells.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.