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>   home   >   Products   >   Primary Antibodies   >   ERAB/HCD2 Antibody   

ERAB/HCD2 Antibody

Rabbit Polyclonal Antibody

  • WB - ERAB/HCD2 Antibody ABV10200
    Western blot analysis of ERAB/HCD2 using rat kidney tissue lysate (Lane 1), mouse 3T3 cell lysate (Lane 2) and Jurkat cell lysate (Lane 3 & 4).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O70351
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 27246 Da
Additional Information
Gene ID 63864
Positive Control Rat kidney tissue lysate, mouse 3T3 cell lysate, and Jurkat cell lysate
Application & Usage The antibody can be used for Western blot analysis (1-4 µg/ml). However, the optimal conditions should be determined individually. Blocking peptide is available separately.
Other Names 3-hydroxyacyl-CoA dehydrogenase type-2
Target/Specificity ERAB/HCD2
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5 mg/ml) affinity purified rabbit anti-ERAB/HCD2 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsERAB/HCD2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Hsd17b10
Synonyms Erab, Hadh2
Function Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/TRMT10C, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. Catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone. Catalyzes the third step in the beta-oxidation of fatty acids. Carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids. Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids (By similarity).
Cellular Location Mitochondrion.
Citations (0)

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ERAB/HCD2 (Hydroxyacyl-Coenzyme A dehydrogenase) is a mitochondrial protein that catalyzes the oxidation of straight-chain 3-hydroxyacyl-CoAs as part of the beta-oxidation pathway. ERAB is characterized as a NAD+-dependent dehydrogenase that overexpressed in neurons affected with Alzheimer’s disease.

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$ 245.00
Cat# ABV10200
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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