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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   alpha-Fodrin Antibody   

alpha-Fodrin Antibody

Rabbit Polyclonal Antibody

  • WB - alpha-Fodrin Antibody ABV10209
    Western blot analysis of α -Fodrin in HeLa cell extract.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P16546
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 284597 Da
Additional Information
Application & Usage Western blot analysis (0.5-4 µg/ml) and in in Immunohistochemistry (10-20 µg/ml).
Other Names SPTAN1, FLJ44613, SPTA2,
Target/Specificity Fodrin
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5 mg/ml) affinity purified rabbit anti-α-Fodrin polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
Precautionsalpha-Fodrin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Sptan1
Synonyms Spna2, Spta2
Function Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.
Cellular Location Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Note=Expressed along the cell membrane in podocytes and presumptive tubule cells during glomerulogenesis and is expressed along lateral cell margins in tubule cells.
Research Areas
Citations (0)

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Fodrin is a universally expressed membrane-associated cytoskeletal protein consisting of α- and β-subunits. The protein is important for maintaining normal membrane structure and supporting cell surface protein function. α-Fodrin is one of the important targets cleaved by caspases during apoptosis. The full length 240 kDa protein can be cleaved at several sites within its sequence by activated caspases generating N-terminal 150 kDa, C-terminal 120 kDa, and 35 kDa major products. Cleavage of α-Fodrin leads to membrane malfunction and cell shrinkage.

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$ 245.00
Cat# ABV10209
(40 western blots)
Availability: 5-7days
Bulk Size
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