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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CaMKII Antibody   

CaMKII Antibody

Rabbit Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UQM7
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 54088 Da
Additional Information
Gene ID 815
Application & Usage Western blotting at 1-2 µg/ml. However, the optimal concentrations should be determined individually. The anti-CaMKII antibody recognizes the 50 kDa of CamonkeyII in samples from human, mouse, and rat origins.
Other Names CAMK2A , CAMKA , KIAA0968, EC
Target/Specificity CaMKII
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5 mg/ml) purified rabbit polyclonal anti-CaMKII antibody in phosphate-buffered saline (PBS) containing 50% glycerol, 1% BSA, and 0.02% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsCaMKII Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CAMKA, KIAA0968
Function CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity).
Cellular Location Cell junction, synapse, presynaptic cell membrane. Cell junction, synapse Note=Postsynaptic lipid rafts.
Research Areas
Citations (0)

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CaMKII is a member of calcium/calmodulin-activated kinase, functioning in neural synaptic stimulation and T-cell receptor signaling. CaMKII has catalytic and regulatory domains. The binding of Ca++/calmodulin to its regulatory domain releases its autoinhibitory effect and activates the kinase. The activated CaMKII further autophosphorylates itself at Thr286 to render the kinase constitutively active.

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$ 265.00
Cat# ABV10279
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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