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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Hsp105 Antibody   

Hsp105 Antibody

Rabbit Polyclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, IP
Primary Accession Q92598
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 96865 Da
Additional Information
Gene ID 10808
Application & Usage Western blotting (0.5-4 µg/ml), immunoprecipitation (10-20 µg/ml) and Immunohistochemistry (10-20 µg/ml). However, the optimal concentrations should be determined individually.
Other Names HSP 110 family, HSP 105 famioy, heat shock protein
Target/Specificity Hsp105
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.2 mg/ml) Protein A purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsHsp105 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HSPH1
Synonyms HSP105, HSP110, KIAA0201
Function Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities (By similarity).
Cellular Location Cytoplasm.
Tissue Location Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells.
Research Areas
Citations (0)

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Background

Heat shock proteins (HSPs) are ubiquitously expressed in all organisms. The HSPs fall into five general families: HSP105, HSP90, HSP70, the low molecular weight HSPs, and the immunophilins. The HSP105 (also called HSP110) family is composed of HSP105, Apg-1 and Apg-2. The HSP90 family consists of HSP90α, HSP90β and GRP94. The HSP70 family is comprised of HSP70, HSC70, GRP78 and GRP75. The low molecular weight HSPs includes HSP10, HSP25, HSP27 and HSP32. HSP56 and FKBP12 are immunophilins and bind to immunosuppressive dr µgs.

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$ 89.00
$ 265.00
Cat# ABV10285-30
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