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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Heme Oxygenase-1 Antibody   

Heme Oxygenase-1 Antibody

Rabbit Polyclonal Antibody

  • WB - Heme Oxygenase-1 Antibody ABV10286
    Western blot analysis of HO-1 expression in Jurkat cell lysate.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P09601
Reactivity Human, Mouse, Rat, Rabbit, Hamster, Monkey
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 32819 Da
Additional Information
Gene ID 3162
Application & Usage Western blotting (0.5-2 µg/ml), immunoprecipitation (10-20 µg/ml), and Immunohistochemistry (10-20 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes ~32-35 kDa Heme-Oxygenase-1. Jurkat cell lysate can be used as a positive control.
Other Names HMOX1 , HO , HO-1 , HO1 , OTTHUMP00000028925 , bK286B10 , EC
Target/Specificity Heme Oxygenase-1
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsHeme Oxygenase-1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HMOX1
Synonyms HO, HO1
Function Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis.
Cellular Location Microsome. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side
Tissue Location Expressed at higher levels in renal cancer tissue than in normal tissue (at protein level)
Research Areas
Citations (0)

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Heme oxygenase-1 (HO-1) or HSP32 is the inducible isoform of heme oxygenase which catalyzes the NADPH, O2 and cytochrome P450 reductase dependent oxidation of heme to carbon monoxide, iron and biliverdin that is immediately reduced to bilirubin. To date, three heme oxygenase isoforms HO-1, HO-2 and HO-3 have been identified.

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$ 265.00
Cat# ABV10286
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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