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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   Bcl-3 Antibody   

Bcl-3 Antibody

Rabbit Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P20749
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 47584 Da
Additional Information
Gene ID 602
Application & Usage Western blot analysis (2-4 µg/ml). Per researchers feedback, the antibody also works well in Immunoprecipation (10-20 µg/ml), and Immunohistochemistry (20-40 µg/ml). However, the optimal conditions should be determined individually. Detects 55-60 kDa Bcl-3 of human, mouse, and rat origins. Other species have not been tested.
Other Names BCL3 , D19S37 , BCL4
Target/Specificity Bcl-3
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.2 mg/ml) Protein G affinity purified rabbit anti-Bcl-3 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsBcl-3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name BCL3
Synonyms BCL4, D19S37
Function Contributes to the regulation of transcriptional activation of NF-kappa-B target genes. In the cytoplasm, inhibits the nuclear translocation of the NF-kappa-B p50 subunit. In the nucleus, acts as transcriptional activator that promotes transcription of NF-kappa-B target genes. Contributes to the regulation of cell proliferation (By similarity).
Cellular Location Nucleus. Cytoplasm. Cytoplasm, perinuclear region. Note=Ubiquitination via 'Lys- 63'-linked ubiquitin chains is required for nuclear accumulation
Research Areas
Citations (0)

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Bcl-3, a proto-oncogene, is believed to be involved in certain human B cell leukemias. It encodes a protein that functions as an IkB-like molecule for native NFkB, but is specific for the p50 subunit of NFkB.

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$ 265.00
Cat# ABV10295
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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