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CCR1 Antibody

Rabbit Polyclonal Antibody

  • WB - CCR1 Antibody ABV10302
    Western blot analsysis of CCR1 in Jurkat cell lysate.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P32246
Reactivity Human, Mouse, Monkey
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 41173 Da
Additional Information
Gene ID 1230
Application & Usage Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. The anti-CCR1 antibody recognizes 42 kDa human and monkey CCR1 and in a lesser extent the mouse CCR1 in Western blot analysis.
Other Names CMKBR1 , CMKR1 , CD191 , CKR-1 , HM145 , MIP1aR , C-C chemokine receptor type 1
Target/Specificity CCR1
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsCCR1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CCR1
Synonyms CMKBR1, CMKR1, SCYAR1
Function Receptor for a C-C type chemokine. Binds to MIP-1-alpha, MIP-1-delta, RANTES, and MCP-3 and, less efficiently, to MIP-1- beta or MCP-1 and subsequently transduces a signal by increasing the intracellular calcium ions level. Responsible for affecting stem cell proliferation.
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Widely expressed in different hematopoietic cells
Research Areas
Citations (0)

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Chemokines play an important role in inflammation and are critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors. The ever-growing chemokine receptor subtypes can be divided into 2 major groups, CXCR and CCR, based on the 2 major classes of chemokines. One of the CCR receptors, CCR1, is expressed on neutrophils, monocytes, lymphocytes, and eosinophils and binds the leukocyte chemoattractant and hemopoiesis regulator macrophage-inflammatory protein (MIP-1 ), eotaxin, as well as several other related chemokines. Mice lacking the chemokine receptor CCR1 have defects in neutrophil trafficking and proliferation.

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$ 265.00
Cat# ABV10302
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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