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>   home   >   Products   >   Primary Antibodies   >   JMJD1C Antibody   

JMJD1C Antibody

Rabbit Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q15652
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 284525 Da
Additional Information
Gene ID 221037
Application & Usage Western blotting (1 - 4 µg/ml). However, the optimal conditions should be determined individually. The antibody detects JMJ1DC of human origin. Reactivity to other species has not been tested.
Other Names JmjC domain-containing histone demethylation protein 2C, jumonji domain-containing protein 1C, thyroid receptor-interacting protein 8, TRIP-8, TRIP8, JHDM2C, FLJ14374, RP11-10C13.2, DKFZp761F0118, KIAA1380
Target/Specificity JMJD1C
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5 mg/ml) affinity purified rabbit anti- JMJDC1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsJMJD1C Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms JHDM2C, KIAA1380, TRIP8
Function Probable histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May be involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes (By similarity).
Cellular Location Nucleus.
Citations (0)

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JMJD1C is a member of the jumonji (jmj) domain containing gene family of histone demethylases that plays a role in chromatin regulation and influences transcriptional activation and suppression. Some recently characterized members of the jmj family include JARID1A/RBP2, JARID1C, JMJD1A, JMJD1B, JMJD1C, JMJD2A, JMJD2C and JMJD2D. JMJD1C has been identified as a nuclear-receptor coactivator and is a candidate gene for autism.

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$ 265.00
$ 89.00
Cat# ABV10318
(40 western blots)
Availability: 5-7days
Bulk Size
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