Cystatin B Antibody (Clone RJMW2E7)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC |
---|---|
Primary Accession | P04080 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Isotype | Mouse IgG1 |
Clone Names | RJMW2E7 |
Calculated MW | 11140 Da |
Gene ID | 1476 |
---|---|
Application & Usage | Western blotting (0.5-4 µg/ml) and Immunohistochemistry (10-20 µg/ml). However, the optimal conditions should be determined individually. Recognizes human cystatin B. Does not cross-react with cystatin A. |
Other Names | Cystatin-B, CPI-B, Liver thiol proteinase inhibitor, Stefin-B, CSTB, CST6, STFB |
Target/Specificity | Cystatin B |
Antibody Form | Liquid |
Appearance | Colorless liquid |
Formulation | 100 µg Protein G purified mouse anti-Cystatin B monoclonal antibody (mouse IgG1) in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal. |
Handling | The antibody solution should be gently mixed before use. |
Reconstitution & Storage | -20 °C |
Background Descriptions | |
Precautions | Cystatin B Antibody (Clone RJMW2E7) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CSTB |
---|---|
Synonyms | CST6, STFB |
Function | This is an intracellular thiol proteinase inhibitor. Tightly binding reversible inhibitor of cathepsins L, H and B. |
Cellular Location | Cytoplasm. Nucleus |
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Provided below are standard protocols that you may find useful for product applications.
Background
Cystatin B (stefin B, NCPI) is a natural inhibitor of lysosomal cysteine proteases (cathepsins). Its expression seems to be connected to the regulation of proteolysis which is essential for many physiological and pathological processes.
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