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>   home   >   Products   >   Primary Antibodies   >   Metabolism   >   Fis1 Antibody   

Fis1 Antibody

Rabbit Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Y3D6
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 16938 Da
Additional Information
Gene ID 51024
Positive Control IHC: Tonsil tissue
Application & Usage Western blotting (1:100-500), immunoprecipitation (1:50-200), Immunohistochemistry (1:100) and immunofluorescence (1:20-100). However, the optimal concentrations should be determined individually. The antibody recognizes Fis1 of human, mouse, and rat origins.
Other Names hFis1 , TTC11 , H_NH0132A01.6 , CGI-135
Target/Specificity Fis1
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µl purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 20% glycerol, 0.2% BSA, and 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsFis1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FIS1
Synonyms TTC11
Function Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin- related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission.
Cellular Location Mitochondrion outer membrane; Single-pass membrane protein. Peroxisome membrane; Single-pass membrane protein
Research Areas
Citations (0)

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hFis1 is a novel molecule that was discovered as part of the mammalian fission machinery. Fis 1 has been s µggested to play a role in regulation of the fission processes that might be involved in apoptotic mechanisms.

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$ 285.00
Cat# ABV10361
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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