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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Hsp47 Antibody   

Hsp47 Antibody

Rabbit Polyclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, IP
Primary Accession P19324
Reactivity Human, Mouse, Rat, Chicken
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 46534 Da
Additional Information
Gene ID 12406
Application & Usage Western blotting (0.5-4 µg/ml), immunoprecipitation (10-20 µg/ml) and Immunohistochemistry (10-20 µg/ml) in frozen or paraffin embedded tissues. However, the optimal concentrations should be determined individually. The antibody recognizes 47 kDa Hsp47 of human, mouse, rat, and chick origins. Mouse small intestine tissue lysate can be used as a positive control.
Other Names SERPINH1 , AsTP3 , CBP1 , CBP2 , HSP47 , PIG14 , RA-A47 , PPROM , colligen , colligin-2 , SERPINH2
Target/Specificity Hsp47
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.2 mg/ml) Protein A purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsHsp47 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Serpinh1
Synonyms Cbp1, Hsp47
Function Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen.
Cellular Location Endoplasmic reticulum lumen.
Research Areas
Citations (0)
citation

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Background

Heat shock proteins (HSPs) are ubiquitously expressed in all organisms. HSP47 is a molecule expressed constitutively in cells that synthesizes collagen. HSP47 is a procollagen-specific molecular chaperon that resides in the endoplasmic reticulum of procollagen-producing cells and is essential for secretion of procollagen from cells. Significantly, HSP47 plays a vital role in folding and assembling collagen. HSP47 is also known as colligin 1, serpinh1, collagen-binding protein 1 (CBP1) and gp46. The human HSP 47 gene encodes a 47 kDa protein.

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Discontinued
Cat# ABV10366-30
Size:

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