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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Phospho-c-Jun (Ser73) Antibody   

Phospho-c-Jun (Ser73) Antibody

Rabbit Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P05412
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 35676 Da
Additional Information
Gene ID 3725
Application & Usage Western blot analysis (1 µg/ml) and Immunohistochemistry (10-20 µg/ml). However, the optimal conditions should be determined individually. The Phospho-c-Jun (Ser73) antibody detects only activated c-Jun when phosphorylated at Ser73. It does not react with non-phosphorylated c-Jun.

Other Names JUN , AP1 , p39 , c-Jun
Target/Specificity c-Jun, Phospho
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5 mg/ml) affinity-purified rabbit polyclonal phospho-c-Jun (Ser73) antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsPhospho-c-Jun (Ser73) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name JUN
Function Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.
Cellular Location Nucleus.
Research Areas
Citations (0)

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c-Jun is a component of the transcription factor AP-1 that binds and activates transcription at TRE/AP-1 elements. The transcriptional activity of c-Jun is regulated by phosphorylation at Ser63 and Ser73. Extracellular signals, such as growth factors and UV irradiation, stimulate phosphorylation of c-Jun at Ser63/73 and activate c-Jun dependent transcription. The MAP kinase homologue, SAPK/JNK, binds to the N-terminal region of c-Jun and phosphorylates c-Jun at Ser63/73.

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$ 345.00
Cat# ABV10371
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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