|Reactivity||Human, Mouse, Rat|
|Application & Usage||Western blotting (1-4 µg/ml). However, the optimal conditions should be determined individually. The antibody detects BRD8 in Human, mouse and rat samples.|
|Other Names||Bromodomain-containing protein 8, SMAP, SMAP2, Skeletal muscle abundant protein, Skeletal muscle abundant protein 2, p120, thyroid receptor coactivating protein 120 kDa, TrCP120.|
|Formulation||100 µg (0.5 mg/ml) affinity purified rabbit anti- BRD8 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal.|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||BRD8 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
BRD8 interacts with thyroid hormone receptor in a ligand-dependent manner and enhances thyroid hormone-dependent activation from thyroid response elements. BRD8 contains a bromodomain and is tho µght to be a nuclear receptor coactivator. Three alternatively spliced BRD8 transcript variants that encode distinct BRD8 isoforms have been identified.
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