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ACAA1 Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q921H8 |
| Other Accession | AAH12400.1 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 43953 Da |
| Gene ID | 113868 |
|---|---|
| Positive Control | Jurkat cell lysate and rat kidney tissue lysate |
| Application & Usage | Western Blot analysis (1-4 µg/ml). However, the optimal concentrations should be determined individually. Blocking peptide is available separately. |
| Other Names | Acetyl-CoA acyltransferase A, Beta-ketothiolase A, |
| Target/Specificity | ACAA1 |
| Antibody Form | Liquid |
| Appearance | Colorless liquid |
| Formulation | 100 µg (0.5 mg/ml) affinity purified rabbit anti-ACAA1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal. |
| Handling | The antibody solution should be gently mixed before use. |
| Reconstitution & Storage | -20 °C |
| Background Descriptions | |
| Precautions | ACAA1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Acaa1a {ECO:0000312|MGI:MGI:2148491} |
|---|---|
| Synonyms | Acaa1 |
| Function | Responsible for the thiolytic cleavage of straight chain 3- keto fatty acyl-CoAs (3-oxoacyl-CoAs) (Probable). Plays an important role in fatty acid peroxisomal beta-oxidation (Probable). Catalyzes the cleavage of short, medium, long, and very long straight chain 3- oxoacyl-CoAs (By similarity). |
| Cellular Location | Peroxisome {ECO:0000250|UniProtKB:P09110}. Note=Transported into peroxisomes following association with PEX7 {ECO:0000250|UniProtKB:P09110} |
| Tissue Location | Mainly expressed in liver and intestine. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
ACAA1 (acetylCoenzyme A acyltransferase 1), catalyzes the conversion of acyl-CoA and acetyl-CoA to 3-oxoacyl-CoA in the fatty acid oxidation pathway. Deficiency of this enzyme can lead to pseudo-Zellweger syndrome.
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