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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   TLR9 Antibody   

TLR9 Antibody

Rabbit Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9EQU3
Other Accession NP_112455
Reactivity Human, Mouse, Rat, Pig
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 116412 Da
Additional Information
Gene ID 81897
Application & Usage Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~113 kDa of full length and the 65 kDa cleaved fragment in Jurkat cell lysate. Reactivity to other species has not been tested.
Other Names Toll-like receptor 9
Target/Specificity TLR9
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsTLR9 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Tlr9
Function Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Plays a role in defense against systemic mouse cytomegalovirus infection. Controls lymphocyte response to Helicobacter infection.
Cellular Location Endoplasmic reticulum membrane; Single-pass type I membrane protein. Endosome. Lysosome. Cytoplasmic vesicle, phagosome. Note=Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist
Tissue Location Expressed in the basolateral region of gastric epithelial cells with high levels detected in antrum and body mucosa (at protein level). Detected in spleen and stomach at higher levels in C57BL/6 mice than BALB/C
Research Areas
Citations (0)

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The Toll-like receptor (TLR) family of proteins are characterized by a highly conserved Toll homology (TH) domain, which is essential for Toll-induced signal transduction. TLR9 has been s µggested as a receptor for unmethylated CpG dinucleotides in the bacterial DNA. TLR9 is highly expressed in the spleen.

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$ 245.00
Cat# ABV10411
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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