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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   TROY/TAJ Antibody   

TROY/TAJ Antibody

Rabbit Polyclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q9JLL3
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 45265 Da
Additional Information
Gene ID 29820
Application & Usage Western blotting (1-4 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes mouse TROY. Reactivity to other species has not been tested.
Other Names TAJ alpha , TAJ , TNFRSF 19 , TRADE , Tnfrsf19 , AL023044 , AW123854 , TRADE , Tnfrsf20 , Troy
Target/Specificity TROY/TAJ
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5 mg/ml) rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsTROY/TAJ Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Tnfrsf19
Synonyms Taj, Troy
Function Can mediate activation of c-Jun and NF-kappa-B. May promote caspase-independent cell death (By similarity). Isoform 2 and isoform 3 may act as decoy receptors.
Cellular Location [Isoform 1]: Cell membrane; Single- pass type I membrane protein [Isoform 4]: Cell membrane; Single- pass type I membrane protein
Tissue Location Highly expressed in adult brain, and in embryos from day 11-17, but not earlier. Detected in embryonic brain and epithelium, and at lower levels in adult heart, lung and liver. In neonatal mice, mainly in hair follicles and neuron-like cells in the cerebellum, but not in the skin epidermis. Isoform 3 was found in embryonic day 17.5 skin but not in brain and liver
Research Areas
Citations (0)
citation

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Background

TROY (also designated TAJ), a member of the TNFR superfamily, exists as several isoforms that vary in functions. Full length TROY contains a cytoplasmic tail, which recruits tumor necrosis factor receptor-associated factor (TRAF) 2. The interaction between TROY and TRAF2 promotes cell survival thro µgh the NFκB signaling pathway. One truncated version of TROY, designated TNFRSF19, contains a shortened cytoplasmic tail, which prevents TNFRSF19 from activating the NFκB signal transduction pathway.

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Discontinued
Cat# ABV10413-30
Size:

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