|Application & Usage||Western blot analysis (1-4 µg/ml). However, the optimal conditions should be determined individually.|
|Other Names||TNFSF12 , TWEAK , MGC20669 , MGC129581 , DR3LG ,|
|Formulation||100 µg (0.5 mg/ml) antigen affinity purified rabbit anti-human TWEAKR polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||TreakR Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
TWEAK is a member of the TNF family and was first described as a weak inducer of apoptosis in demonstrates that this relatively small molecule is a fully transformed cell lines. Recently, a receptor for TWEAK was isolated by expression cloning from a HUVEC cell cDNA library. TweakR is a small protein belonging to TNF receptor super family. TweakR is capable of intiating a proliferative signal by biding to TRAF1, 2, and 3. TweakR mRNA is upregulated during tissue regeneration in aorta and liver. It may also play a role in vascular cell migration and angiogenesis.
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