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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   Galectin-3 Antibody   

Galectin-3 Antibody

Rabbit Polyclonal Antibody

  • WB - Galectin-3 Antibody ABV10437
    Western Blot Analysis of Galectin-3 expression with Jurkat Cell Lysate.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P08699
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 27202 Da
Additional Information
Gene ID 83781
Application & Usage Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. Jurkat cell lysate can be used as a positive control. The antibody recognizes the 30 kDa human Galectin-3 in Western blot analysis with Jurkat cell lysate.
Other Names LGALS3 , L-31 , GAL3 , GALIG , MAC2 , GALBP , LGALS2 , MAC-2 , CBP35
Target/Specificity Galectin 3
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.2 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsGalectin-3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Lgals3
Function Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells (By similarity). Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis.
Cellular Location Cytoplasm. Nucleus. Secreted. Note=Secreted by a non- classical secretory pathway and associates with the cell surface
Research Areas
Citations (0)

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Galectins are a family of soluble β-galactoside-binding animal lectins that modulate cell-to-cell and cell-to-ECM interactions, as well as apoptosis. Galectin-3 encodes a 30-35 kDa protein containing a single carbohydrate binding domain, which binds galactose-containing glycoconj µgates. Upregulated expression of Galectin-3 is involved in cancer progression and metastasis.

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$ 245.00
Cat# ABV10437
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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