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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Galectin-1 Antibody   

Galectin-1 Antibody

Rabbit Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P09382
Other Accession AAP36586
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 14716 Da
Additional Information
Gene ID 3956
Application & Usage Western blotting (0.5 – 2.0 µg/ml) and Immunohistochemistry (5 µg/ml). However, the optimal concentrations should be determined individually.
Other Names Galaptin, Galectin1 , DKFZp686E23103
Target/Specificity Galectin 1
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5mg/ml) antigen affinity purified rabbit anti-human Galectin-1 polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.1% BSA, and 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsGalectin-1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis.
Cellular Location Secreted, extracellular space, extracellular matrix
Tissue Location Expressed in placenta, maternal decidua and fetal membranes. Within placenta, expressed in trophoblasts, stromal cells, villous endothelium, syncytiotrophoblast apical membrane and villous stroma. Within fetal membranes, expressed in amnion, chorioamniotic mesenchyma and chorion (at protein level) Expressed in cardiac, smooth, and skeletal muscle, neurons, thymus, kidney and hematopoietic cells
Research Areas
Citations (0)

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Galectins are a family of soluble β-galactoside-binding animal lectins that modulate cell-to-cell and cell-to-ECM interactions, as well as apoptosis. Galectin-1 has the ability to induce apoptosis of activated T-cells and T-leukaemia cell lines. Other activities include cell differentiation and inhibition activity of CD45 protein phosphatase activity. Galectin also binds beta-galactoside as well as CD45, CD3 and CD4. Human Galectin is a 14.5 kDa protein consisting of 134 amino acid residues.

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$ 245.00
Cat# ABV10442
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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