|Calculated MW||102580 Da|
|Application & Usage||Western blotting (1-4 µg/ml). However, the optimal conditions should be determined individually. The antibody detects the ROBO4 band in human samples. |
|Other Names||UNQ421/PRO3674, ECSM4, FLJ20798, MGC133352, MGC133353, MRB|
|Formulation||100 µg (0.5 mg/ml) affinity purified rabbit anti- ROBO4polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal.|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||ROBO4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migration by Slit proteins (By similarity).|
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Provided below are standard protocols that you may find useful for product applications.
ROBO4 contains two fibronectin type-III domains and two Ig-like C2-type domains. ROBO4 is predominantly expressed in vascular endothelium and is considered important for vascular development. ROBO4 is a receptor for Slit proteins and may mediate the inhibition of primary endothelial cell migration by Slit proteins.
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