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Syndecan-1 Antibody

Rabbit Polyclonal Antibody

     
  • WB - Syndecan-1 Antibody ABV10485-30
    Western blot analysis of Syndecan-1 in 3T3 cell lysate.
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P18827
Reactivity Human, Mouse, Rat, Hamster
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 32462 Da
Additional Information
Gene ID 6382
Application & Usage Western blotting (0.5-4 µg/ml), However, the optimal conditions should be determined individually. Other applications have not been tested. The antibody detects ~100 kDa Syndecan-1 from samples of human, mouse, rat, and hamster origins. Cross-reactivity to other species has not been determined.
Other Names SYND1 , SYND 1 , SDC1 , CD138 , CD138 , CD 138 , Syndecan1 , Syndecan 1 , SDC
Target/Specificity Syndecan-1
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5 mg/ml) affinity purified rabbit anti-Syndecan-1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsSyndecan-1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SDC1
Synonyms SDC
Function Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP (PubMed:22660413).
Cellular Location Membrane; Single-pass type I membrane protein. Secreted. Secreted, exosome. Note=Shedding of the ectodomain produces a soluble form.
Research Areas
Citations (0)

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Background

Syndecans are type I integral membrane proteoglycans that are involved in cell-extracellular matrix adhesion and growth factor binding. Syndecan-1 is a matrix receptor which binds to Collagens, Fibronectin and Thrombospondin. Syndecan-1 and Syndecan-3 interact with MK (midkine), a growth/differentiation factor involved in embryogenesis. Syndecan-2 is highly expressed at areas of high morphogenetic activity, such as epithelial-mesenchymal interfaces and the prechondrogenic and preosteogenic mesenchymal condensations. Syndecan-4 functions cooperatively with integrins in the processes of cell spreading and focal adhesion assembly.

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$ 89.00
$ 285.00
Cat# ABV10485-30
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