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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   EMR2 Antibody   

EMR2 Antibody

Rabbit Polyclonal Antibody

  • WB - EMR2 Antibody ABV10494
    Western blot analysis of EMR2 in Jurkat cell lysate (Lane 1 & 2).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UHX3
Other Accession A0JNV7
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 90472 Da
Additional Information
Gene ID 30817
Positive Control Jurkat cell lysate
Application & Usage The antibody can be used in Western Blot analysis (1-4 µg/ml). However, the optimal concentrations should be determined individually. Blocking peptide is available separately.
Other Names EGF-like module receptor 2, CD312
Target/Specificity EMR2
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5 mg/ml) affinity purified rabbit anti- EMR2polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsEMR2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name EMR2
Function Cell surface receptor that binds to the chondroitin sulfate moiety of glycosaminoglycan chains and promotes cell attachment. Promotes granulocyte chemotaxis, degranulation and adhesion. In macrophages, promotes the release of inflammatory cytokines, including IL8 and TNF.
Cellular Location Cell membrane; Multi-pass membrane protein. Cell projection, ruffle membrane; Multi-pass membrane protein Note=Localized at the leading edge of migrating cells
Tissue Location Expression is restricted to myeloid cells. Highest expression was found in peripheral blood leukocytes, followed by spleen and lymph nodes, with intermediate to low levels in thymus, bone marrow, fetal liver, placenta, and lung, and no expression in heart, brain, skeletal muscle, kidney, or pancreas. Expression is also detected in monocyte/macrophage and Jurkat cell lines but not in other cell lines tested
Research Areas
Citations (0)

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EGF-like module-containing mucin-like receptor 2 (EMR2) is a member of the class B seven-span transmembrane (TM7) receptor family. EMR2 is expressed predominantly by cells of the immune system such as leukocytes. EMR2 is proteo-lytically cleaved into two subunits: a seven-transmembrane subunit, and an extracellular α subunit.

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$ 245.00
Cat# ABV10494
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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