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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   MEF2A Antibody   

MEF2A Antibody

Rabbit Polyclonal Antibody

  • WB - MEF2A Antibody ABV10515
    Western blot analysis of MEF2A expression in C2C12 cells.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q02078
Other Accession AAH13437
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 54811 Da
Additional Information
Gene ID 4205
Application & Usage Western blotting (1-4 µg/ml). The optimal concentrations should be determined individually. A ~55 kDa band should be detected.
Other Names MEF2A , MEF2 , RSRFlow cytometry9 , RSRFlow cytometry4 , ADCAD1
Target/Specificity MEF2A
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5 mg/ml) peptide affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 50% glycerol, 1% BSA, and 0.02% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsMEF2A Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MEF2A
Synonyms MEF2
Function Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle- specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with chromatin to the ZNF16 promoter.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00251, ECO:0000269|PubMed:12691662, ECO:0000269|PubMed:16563226}
Tissue Location Isoform MEF2 and isoform MEFA are expressed only in skeletal and cardiac muscle and in the brain. Isoform RSRFC4 and isoform RSRFC9 are expressed in all tissues examined
Research Areas
Citations (0)

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MEF2A is a member of MEF2 (myocyte enhancer factor 2) family of transcription factors. P38 phosphorylates MEF2A at Thr312 and Thr319 within the transcription activation domain and these phosphorylation events promote MEF2A –MEF2D heterodimer dependent gene expression.

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$ 265.00
Cat# ABV10515
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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