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Dvl3 Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q61062 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 78123 Da |
| Gene ID | 13544 |
|---|---|
| Application & Usage | Western blotting (0.5-4 µg/ml). The optimal concentrations should be determined individually. A ~80 kDa band and a smaller ~45 kDa cleavage fragment can be detected. |
| Other Names | DVL3 , KIAA0208 , Dishevelled-3, Dishevelled3 |
| Target/Specificity | Dvl3 |
| Antibody Form | Liquid |
| Appearance | Colorless liquid |
| Formulation | 100 µg (0.5 mg/ml) peptide affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal. |
| Handling | The antibody solution should be gently mixed before use. |
| Reconstitution & Storage | -20 °C |
| Background Descriptions | |
| Precautions | Dvl3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Dvl3 |
|---|---|
| Function | Involved in the signal transduction pathway mediated by multiple Wnt genes. |
| Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:O14641}. |
| Tissue Location | Ubiquitous. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Dvl1, Dvl2, and Dvl3 are mammalian homologs of Dsh (disheveled) proteins that are involved in Wnt signaling pathways. Upon treatment with Wnt proteins, Dvls become hyperphosphorylated and accumulate in the nucleus. Dvls have been reported to mediate endocytosis and may also play a role in certain cancers.
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