|Reactivity||Human, Mouse, Rat|
|Calculated MW||74141 Da|
|Application & Usage||Western blotting (0.5-4 µg/ml). The optimal concentrations should be determined individually. The antibody detects the 73 kDa full length HDC in samples from human, mouse and rat origins. It does not cross react with DOPA decarboxylase (DDC).|
|Other Names||Histidine decarboxylase|
|Formulation||100 µg (0.2 mg/ml) protein A affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||HDC Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the biosynthesis of histamine from histidine.|
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Provided below are standard protocols that you may find useful for product applications.
Histidine decarboxylase (HDC) is the enzyme catalyzing the conversion of histidine into histamine. HDC can be found in the histamine secreting ECL cells of some species as well as in the mast cells.
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