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HAT-2 Antibody

Rabbit Polyclonal Antibody

  • WB - HAT-2 Antibody ABV10525
    Western blot analysis of HAT-2 expression in Jurkat cell lysate.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O95251
Other Accession AAH32640
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 70642 Da
Additional Information
Gene ID 11143
Application & Usage Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes ~65 kDa HAT-2 from human samples, and in a lesser extent, from mouse and rat samples. Jurkat cell lysate can be used as a positive control.
Other Names Anti-HAT-2 antibody, HAT-2 antibody, Anti-HAT-2, HAT-2, HAT, histone acetyltransferase, HATs, HDACs HAT-2 Polyclonal Antibody, Anti-HAT-2
Target/Specificity HAT2
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5 mg/ml) Protein A affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsHAT-2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KAT7
Synonyms HBO1, HBOa, MYST2
Function Component of the HBO1 complex which has a histone H4- specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may regulate DNA replication and act as a coactivator of TP53-dependent transcription. Specifically represses AR-mediated transcription.
Cellular Location Nucleus, nucleoplasm
Tissue Location Ubiquitously expressed, with highest levels in testis.
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Histone acetyltransferases (HATs) have been implicated in a number of cellular functions including gene regulation, DNA synthesis, and repair. Histone acetyltransferases and deacetylases are, respectively, the enzymes devoted to the addition and removal of acetyl groups from lysine residues on the histone N-terminal tails. The enzymes exert fundamental roles in developmental processes and their deregulation has been linked to the progression of diverse human disorders, including cancer.

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$ 245.00
Cat# ABV10525
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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