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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   MAP-1 Antibody   

MAP-1 Antibody

Rabbit Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9ERH6
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 39404 Da
Additional Information
Gene ID 64113
Application & Usage Western blotting (1-4 µg/ml). However, the optimal concentrations should be determined individually. Jurkat cell lysate can be used as positive controls. The antibody recognizes 39 kDa MAP-1 from samples of human, mouse and rat origins. Reactivity to other species has not been determined. In human samples, an additional ~78 kDa dimer can be detected in Jurkat cell lysate. In mouse sample, an additional ~33 kDa cleavage fragment can also be detected in mouse small intestine tissue lysate.
Other Names MAP1 , MAP1A , MAP1L , MTAP1A , FLJ77111
Target/Specificity MAP-1
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5 mg/ml) Protein A affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsMAP-1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Moap1
Function Required for death receptor-dependent apoptosis. When associated with RASSF1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation (By similarity).
Tissue Location Widely expressed, including in the brain. High expression levels in testis.
Research Areas
Citations (0)

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Human MAP-1 (Modulator of Apoptosis Protein) is a novel Bax-associating protein. MAP-1 mediates caspase-dependent apoptosis in mammalian cells when overexpressed. MAP-1 homodimerizes and associates with the proapoptotic Bax and the prosurvival Bcl-2 and Bcl-XL of the Bcl-2 family.

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$ 245.00
Cat# ABV10527
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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