|Reactivity||Human, Mouse, Rat|
|Calculated MW||66786 Da|
|Application & Usage||Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody detects a 68 kDa mouse Lamin B1 on SDS-PAGE immunoblots. It also reacts in a lesser extent with human and rat samples. A ~40 kDa unknown band can also be detected in all human, mouse and rat samples.|
|Other Names||LMB1, LMNB1, LMNB 1, LMNB, LaminB1, LMN|
|Formulation||100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||Lamin B1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.|
|Cellular Location||Nucleus inner membrane; Lipid-anchor; Nucleoplasmic side|
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