|Reactivity||Human, Mouse, Rat|
|Calculated MW||39518 Da|
|Application & Usage||Western Blot analysis (0.5-4.0 µg/ml). However, the optimal condition should be determined individually.|
|Other Names||ECALECTIN , HUAT, LGALS9 , MGC117375 , MGC125973 , MGC125974 , galectin 9 , galectin-9|
|Formulation||100 µg (0.5 mg/ml) affinity purified rabbit anti-Galectin-9 polyclonal antibody in phosphate (PBS, pH 7.2) containing 30% glycerol, 0.5% BSA and 0.01% thimerosal.|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||Galectin-9 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Binds galactosides. Has high affinity for the Forssman pentasaccharide. May play a role in thymocyte-epithelial interactions relevant to the biology of the thymus. Inhibits cell proliferation. It is a ligand for HAVCR2/TIM3. Induces T-helper type 1 lymphocyte (Th1) death. Isoform Short acts as an eosinophil chemoattractant.|
|Cellular Location||Cytoplasm. Secreted. Note=May also be secreted by a non-classical secretory pathway.|
|Tissue Location||Peripheral blood leukocytes and lymphatic tissues. Overexpressed in Hodgkin disease tissue|
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Provided below are standard protocols that you may find useful for product applications.
Galectin-9 is an eosinophile chemoattractant produced by activated T lymphocytes. It is an integral membrane protein that plays a role in immuno/inflammation processes that causes inflammatory reactions in the central nervous system (CNS). Galectin-9 exists as two isoforms, a long form and a short form, which differ by an internal stretch of 32 amino acids.
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