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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Lipin 2 Antibody   

Lipin 2 Antibody

Rabbit Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q99PI5
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 99613 Da
Additional Information
Gene ID 64898
Application & Usage Western blotting (0.5-4 µg/ml). It detects a band between 70-100 kDa, corresponding to the molecular mass of Lipin-2. A lower band ~55 kDa can also be detected, presumably to be the cleavage fragment of Lipin-2.
Other Names KIAA0249 , LPIN2
Target/Specificity Lipin 2
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsLipin 2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Lpin2
Function Plays important roles in controlling the metabolism of fatty acids at differents levels. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis in the reticulum endoplasmic membrane. Acts also as a nuclear transcriptional coactivator for PPARGC1A to modulate lipid metabolism.
Cellular Location Nucleus. Cytoplasm, cytosol. Endoplasmic reticulum membrane. Note=Translocates from cytosol to endoplasmic reticulum membrane with increasing levels of oleate
Tissue Location Expressed at high level in liver and to some extend in lung, kidney, placenta, spleen, thymus, lymph node, prostate, testes, small intestine, and colon. Expressed also in circulating red blood cells and site of lymphopoiesis
Research Areas
Citations (0)

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Lipin 2 is a nuclear protein that belongs to the evolutionarily conserved Lipin family. Studies show that a mutation to human Lipin 2 is linked to autosomal dominant high grade myopia and Majeed syndrome.

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$ 245.00
Cat# ABV10646
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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