|Reactivity||Human, Mouse, Rat|
|Application & Usage||Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~60-130 kDa DMP- 1 of human, mouse, and rat origins. Reactivity to other species has not been tested. |
|Other Names||DMP-1, DMP 1|
|Formulation||100 µg (0.5 mg/ml) affinity purified rabbit anti-DMP-1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||DMP1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
DMP-1 (Dentin matrix protein1) is a member of the integrin ligand N-linked glycoprotein family.It is mostly found in bone, tooth and hypertrophic cartilage. DMP-1 plays an important role in dentin and bone mineralization. DMP-1 has multiple serine, glutamic acid and aspartic acid residues, a GAG attachement site and RGD motif. DMP-1 is proteolytically proceesed into mulitple fragemtns in the extracellular matrix (ECM) of bone and dentin.
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