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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   Proteinase Inhibitor 6 (PI-6) Antibody (Clone 3A)   

Proteinase Inhibitor 6 (PI-6) Antibody (Clone 3A)

Mouse Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P35237
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype Mouse IgG2b/k
Clone Names 3A
Calculated MW 42622 Da
Additional Information
Gene ID 5269
Application & Usage The antibody can be used in indirect immunofluorescence, immunoprecipitation, and flow cytometry. However, the optimal concentrations should be determined individually.
Other Names CAP, DKFZp686I04222 , MGC111370 , MSTP057 , PI6 , PTI , SERPINB6
Target/Specificity PI6
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5 mg/ml) purified mouse monoclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsProteinase Inhibitor 6 (PI-6) Antibody (Clone 3A) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms PI6, PTI
Function May be involved in the regulation of serine proteinases present in the brain or extravasated from the blood (By similarity). Inhibitor of cathepsin G, kallikrein-8 and thrombin. May play an important role in the inner ear in the protection against leakage of lysosomal content during stress and loss of this protection results in cell death and sensorineural hearing loss.
Cellular Location Cytoplasm
Tissue Location Expressed in keratinocytes (at protein level). Highest levels in skeletal muscle. Also found in placenta, cardiac muscle, lung, liver, kidney and pancreas. Expressed in the inner ear hair cells. Expressed abundantly by normal mast cells in different tissues and by mast cells in mastocytoma lesions
Research Areas
Citations (0)

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Proteinase inhibitor 6 (PI-6) is a 42 kDa cytoplasmic protein belonging to the serine proteinase inhibitor (serpin) super family and the ovalbumin-serpin super family. Sequence similarity s µggests that PI-6 most resembles the ovalbumin serpins . Highest levels of PI-6 are found in skeletal muscle. PI-6 is also found in placenta, cardiac muscle, lung, liver, kidney and pancreas.

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$ 295.00
Cat# ABV10660
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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