|Reactivity||Human, Mouse, Rat|
|Calculated MW||20489 Da|
|Application & Usage||Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. Other applications have not been tested. The antibody recognizes Relaxin-1 (~20 kDa) and its dimer form (~40 kDa) in samples from human, mouse and rat origins. Other species have not been tested.|
|Other Names||H1 , RLN1 , RLXH1 , bA12D24.3.1 , bA12D24.3.2 , preprorelaxin H1 , prorelaxin , relaxin 1 (H1) , relaxin H1|
|Formulation||100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||Relaxin-1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals.|
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Provided below are standard protocols that you may find useful for product applications.
Relaxin is a peptide hormone belonging to the insulin gene superfamily. It is made by the corpora lutea of the ovaries during pregnancy in many mammalian species. The secretion of the hormone into the blood stream just before parturition results in softening and lengthening of the pubic symphysis and a softening of the cervix, which facilitates the process of birth. Relaxin-1 is proteolytically processed into a hetorodimer that has two peptide chains, A and B that are covalently linked by disulfide bonds.
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