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DPP10 Antibody

Rabbit Polyclonal Antibody

  • WB - DPP10 Antibody ABV10695
    Western blot analysis of DPP10 expression in Jurkat cell lysate.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6NXK7
Other Accession AAH63074.4
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 90827 Da
Additional Information
Gene ID 269109
Application & Usage Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~90-97 kDa DPP10 in samples from human, mouse and rat origins.
Other Names DPP-10, DPP 10, Dipeptidyl Peptidase 10, DPPY splice variant c, dipeptidylpeptidase 10
Target/Specificity DPP10
Antibody Form Liquid
Appearance Colorless liquid
Formulation 200 µg (0.5 mg/ml) affinity purified rabbit DPP10 polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsDPP10 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Dpp10
Function Promotes cell surface expression of the potassium channel KCND2 (PubMed:22311982). Modulates the activity and gating characteristics of the potassium channel KCND2 (PubMed:22311982). Has no dipeptidyl aminopeptidase activity (Probable).
Cellular Location Cell membrane; Single-pass type II membrane protein
Tissue Location Detected in brain cortex (at protein level) (PubMed:22311982). Expressed in the brain, predominantly by neurons and not by glia.
Research Areas
Citations (0)

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Dipeptidyl peptidase 10 or DPP10 is a single-pass type II membrane protein that belongs to the S9B family of DPP serine proteases. The conserved serine residue which normally found in the serine proteases family is not present in DPP10. Thus, DPP10 has no detectable proteases activity as the active serine site is replaced by a glycine residue. DPP10 cleaves the terminal dipeptides from cytokines and chemokines and also facilitates the voltage-gated potassium channels. It is expressed mostly in the brain and is a potential target for asthma treatment.

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$ 245.00
Cat# ABV10695
(40 western blots)
Availability: 5-7days
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