|Reactivity||Human, Mouse, Rat|
|Calculated MW||51318 Da|
|Application & Usage||Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~68 kDa of Hemopexin in samples from human, mouse and rat origins. Reactivity to other species has not been tested. |
|Formulation||200 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||Hemopexin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.|
|Tissue Location||Expressed by the liver and secreted in plasma.|
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Provided below are standard protocols that you may find useful for product applications.
Hemopexin (HPX) is a plasma protein that has the highest binding affinity for heme. HPX prevents heme-mediated oxidative stress and heme-bound iron loss by transporting heme to the liver for breakdown.
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